Perifosine
Update:2014-10-30 12:56:42
| Item: | Perifosine | ||
| Synonym: | |||
| CAS No.: | 157716-52-4 | Special Grade: | Biotech Grade |
| Formula: | C25H52NO4P | M.W.: | 461.66 |
Order
| Product No. | Size | Price | Brand |
| S1037-5mg | 5mg | 2980 | |
| S1037-10mg | 10mg | 5690 | |
| S1037-50mg | 50mg | 28520 | |
| S1037-1mg | 1mg | 880 | Sigma |
Introduction
Perifosine抑制Akt，抗肿瘤增生，IC50为0.6–8.9 µM。Perifosine抑制巴西利什曼原虫，亚马逊利什曼原虫，大利什曼原虫，小利什曼原虫，IC50分别为0.79±0.03, 3.62±0.36 , 0.19±0.27, 0.078±0.29μg/ml。 [2] 用替莫唑胺和perifosine处理的肿瘤有最低的Ki-67染色指数(1.7 ± 1 |
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